This slow cooker Mississippi pot roast recipe makes the best tender, flavorful, and juicy beef.

Cooking long and slow in the crockpot infuses the meat with piquant and sweet pepperoncini juice, savory ranch dressing, and salty gravy mix.

No need to fuss over this recipe. Let the slow cooker do its magic.

slow cooker Mississippi pot roast on a plate of mashed potatoes with gravy and carrots

Slow Cooker Mississippi Pot Roast

  • No need to fuss over a roast in the oven, when it is so easy to cook a roast long and slow in the slow cooker.
  • This main dish will please everyone at the table even those on a keto diet.
  • Cooking with the slow cooker is guaranteed to make a roast that is tender and juicy. This is just begging for a side of Irish potatoes and a drizzling of gravy!
ingredients for slow cooker Mississippi pot roast including pot roast, onion, pepperoncini peppers, pepperoncini pepper juices, ranch seasoning, cornstarch, water, butter, and gravy mix

Ingredients and Variations

Beef: This recipe calls for a chuck roast, sometimes labeled as pot roast. This can be a tougher cut of meat, which is why cooking long and slow is the best method to ensure tender meat every time. Generally, there are three cuts of beef to be aware if – chuck, brisket, and round. The chuck tends to be tougher and fattier cut, while the brisket is more tender, and the round roast is very lean. The roast can also be cooked from frozen in the slow cooker and will require the same amount of time.

Seasonings: Pepperoncini is a sweet Italian chili pepper that is canned in oil or water. In this recipe, the juices and the peppers are used to flavor the meat. A package of ranch dressing mix, and gravy mix are also sprinkled over the meat.

Variations: A beef roast can also be replaced with a pork roast, or even chicken! Add some carrots to the slow cooker or even some potatoes.

How to Make Crockpot Mississippi Pot Roast

  1. Sear the meat. This is optional but will help to seal in the juices.
  2. Add the roast to the slow cooker along with the optional onions and pepperoncini juice, as described in the recipe card below.
  3. Sprinkle with gravy mix and ranch dressing mix. Add the peppers. Top with butter.
  4. Cook in the slow cooker on low for 8-10 or on high 4-6 hours.
  5. Remove from slow cooker. Slice, and serve.
pot roast with peppers and juices in a slow cooker for slow cooker Mississippi pot roast

Storing Mississippi Pot Roast

  • Make the pot roast ahead of time. Simply prepare everything in the slow cooker and keep it in the refrigerator until ready for cooking.
  • Leftovers will keep in an airtight container in the refrigerator for up to 4 days. Leftover roast can also be frozen and will keep for 3 months in the freezer.
shredded pot roast with peppers on a plate slow cooker Mississippi pot roast

Leftovers

Reheat leftovers (if there are any) in the oven covered with foil, or in the microwave at short intervals until heated through.

Use leftovers for open faced sandwiches, a substitute for chicken in this recipe for pot pie, or add to a stir fry.

close up image of slow cooker Mississippi pot roast on a fork

Other Delish Beef Entrees!

Have you tried this Slow Cooker Mississippi Pot Roast recipe? Leave a comment and rating below!

slow cooker Mississippi pot roast on a plate of mashed potatoes with gravy and carrots
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Slow Cooker Mississippi Pot Roast

Make this easy slow cooker Mississippi pot roast for juicy and tender beef everytime!
Prep Time 15 minutes
Cook Time 4 hours
Total Time 4 hours 15 minutes
Servings 8 servings
Author Candace

Ingredients  

Optional Gravy:

  • 1-2 Tablespoons cornstarch
  • 1-2 Tablespoons water

Instructions 

  • Optional step: In a large skillet on medium-high heat, sear the roast for 5 minutes on each side.
  • To a slow cooker, add the roast, onion if using, and pepperoncini juice. Sprinkle roast with dressing mix, gravy mix, and peppers. Top with butter slices.
  • Cook 8-10 hours on low or 4-6 hours on high, or until roast is fork-tender. If the roast is not fork tender, cook for another 30 minutes and check again.
  • Remove the roast from the slow cooker.
  • For optional gravy, mix cornstarch and water to create a slurry. Stir slurry into the juices in the slow cooker, cover, and turn to high. Cook for 5-10 minutes, or until slightly thickened.
  • Shred meat with a fork, or slice against the grain. Mix in with the juices if desired, or serve with the gravy. Serve with peppers and juices or gravy along with mashed potatoes, egg noodles, or rice.

Notes

  • Prep everything ahead of time and refrigerate until ready for cooking.
  • Refrigerate leftovers in an airtight container for up to 4 days, they are perfect for sandwiches!
  • Freeze portions in zippered bags for 3 months.
  • Time calculated with slow cooker set on the high setting.
5 from 7 votes↑ Click stars to rate now!
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Nutrition Information

Calories: 480 | Carbohydrates: 5g | Protein: 44g | Fat: 32g | Saturated Fat: 15g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 15g | Trans Fat: 2g | Cholesterol: 172mg | Sodium: 545mg | Potassium: 796mg | Fiber: 1g | Sugar: 1g | Vitamin A: 243IU | Vitamin C: 10mg | Calcium: 47mg | Iron: 5mg

Nutrition information does not include optional ingredients or garnish and is an estimate. It may change based on actual ingredients and cooking methods used.

Course Main Course
Cuisine American

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top image: slow cooker Mississippi pot roast on a bed of mashed potatoes bottom image: ingredients for slow cooker Mississippi pot roast
slow cooker Mississippi pot roast on a plate with mashed potatoes and gravy with writing

Recipe adapted from SpendWithPennies.

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About the author

I am a wife, mother of two, and professional accountant. I love fantastic food, and it is so often the center of our lives, from everyday dinner, to family gatherings, and special evenings at fabulous restaurants. I have always loved cooking and baking, with my mom and grandma, and now, with my daughter and son. I love trying new recipes while enjoying my favorites too. I’m so happy to share them with you.
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