Preheat oven to 350˚F. Line a baking tray with foil and grease the tray (brush with oil or spray with cooking spray).
In a medium bowl, mix together bread crumbs, milk, eggs, onion, 2 Tablespoons chili sauce, Italian dressing mix (or other spices), and pepper. Allow to rest for 10 minutes.
Gently break up ground beef as you add it to the bowl with the bread crumb mixture. Gently mix until well combined and will hold its shape, about 2 minutes.
On the foil lined baking tray, shape beef mixture into a loaf, approximately 9” x 5”.
Bake for 45 minutes.
Combine chili sauce with brown sugar if using. After 45 minutes, spread chili sauce on the meatloaf and bake for 10-15 minutes, until cooked through. The internal temperature should be at least 160F.